A novel pharmaceutical combination comprising a cytotoxic antineoplastic agent selected from a group consisting of paclitaxel, docetaxel, doxorubicin or gemcitabine or a pharmaceutically acceptable salt thereof and at least one cyclin dependent kinase (CDK) inhibitor wherein the said combination exhibits synergistic effects when used in the treatment of cancer. The invention also relates to a method for the treatment of cancer, using a therapeutically effective amount of the said combination.一種新穎醫藥組合,其包含一種由太平洋紫杉醇、紫杉醇、阿霉素或吉西他濱或是其醫藥可接受鹽類所組成族群選出的細胞毒性抗腫瘤劑及至少一種細胞週期依賴激酶(CDK)抑制劑;其中該組合當用於癌症治療時顯現相乘作用。本發明亦關於一種癌症治療方法,其係使用醫療有效量的該組合物。Doxo‧‧‧阿霉素