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COMPLEXES MEDICAMENTEUX COMPRENANT UNE ALPHA-FETOPROTEINE
专利权人:
UNIVERSITY HEALTH NETWORK
发明人:
BELLO , ANGELICA MARA,KOTRA, LAKSHMI P.,PAIGE, CHRISTOPHER JOHN,SHERMAN, IGOR
申请号:
CA2974152
公开号:
CA2974152A1
申请日:
2016.01.26
申请国别(地区):
CA
年份:
2016
代理人:
摘要:
Compositions which comprise a hydrophobic taxane such as paclitaxel are produced by non-covalent complexing between the taxane and alpha-fetoprotein c at a ratio of about 4 moles of taxane per mole of AFP. The complexes are water soluble and suitable for injection. Uses of the compositions for treating a subject presenting with an AFP receptor positive and taxane responsive disease cell are also disclosed.
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