There are disclosed compounds that modulate the activity of inhibitors of apoptosis (lAPs), pharmaceutical compositions containing said compounds and methods of treating proliferative disorders and disorders of dysregulated apoptosis, such as cancer, utilizing the compounds of the invention.Linvention concerne des composés qui modulent lactivité dinhibiteurs de lapoptose (lAP), des compositions pharmaceutiques contenant lesdits composés et des méthodes de traitement de troubles prolifératifs et de troubles caractérisés par un dérèglement de lapoptose, tels que le cancer, au moyen des composés de linvention.