Fabio E. S. Souza,Bahareh Khalili,Annyt Bhattacharyya
申请号:
US16683331
公开号:
US20200079740A1
申请日:
2019.11.14
申请国别(地区):
US
年份:
2020
代理人:
摘要:
The present invention provides a novel crystalline form of Eluxadoline, Eluxadoline Form APO-I, a co-crystal of Eluxadoline and methyl nicotinate, compositions and processes for the preparation thereof, and the use of this crystalline form in the treatment of opioid-modulated disorders, and in particular, gastrointestinal disorders, including irritable bowel syndrome with diarrhea (IBS-D).