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INDAZOLE COMPOUNDS AS IRAK4 INHIBITORS
专利权人:
AURIGENE DISCOVERY TECHNOLOGIES LIMITED
发明人:
GUMMADI, VENKATESHWAR RAO,SAMAJDAR, SUSANTA,GUPTA, AJAY
申请号:
PH12016501338
公开号:
PH12016501338A1
申请日:
2016.07.05
申请国别(地区):
PH
年份:
2016
代理人:
摘要:
The present invention provides indazole compound of formula (I), which are therapeutically useful as kinase inhibitor, particularly IRAK4 inhibitors. wherein Z1, Z2, R1, R2, R3, m and n have the meanings given in the specification, and pharmaceutically acceptable salts or stereoisomers thereof that are useful in the treatment and prevention of diseases or disorder, in particular their use in diseases or disorder mediated by kinase enzyme, particularly IRAK4 enzyme. The present invention also provides pharmaceutical composition comprising at least one of the compounds of compound of formula (I) together with a pharmaceutically acceptable carrier, diluent or excipient therefor.
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