用於荷爾蒙替代療法（ＨＲＴ）之極低劑量固體口服劑型农业专利-农业专业知识服务系统

发明人:: MLETZKO, STEPHAN,莫拉兹克　史帝分,莫拉茲克　史帝分,SCHURMANN, ROLF,史巧曼　劳夫,史巧曼　勞夫,GUDE, KERSTIN,古德　克斯廷,莫拉兹克史帝分,莫拉茲克史帝分,史巧曼劳夫,史巧曼勞夫,古德克斯廷

摘要：: The present invention relates to a solid oral dosage form comprising about 0.5 mg estradiol and about 0.25 mg drospirenone and at least one pharmaceutically acceptable excipient and to the package unit of the dosage form. The solid oral dosage form can be used for preventing, treating or alleviating vasomotor symptoms, lowering the frequency of breakthrough bleedings or increasing the incidence rate of amenorrhea in a woman.本發明係關於一種固體口服劑型，其包含約0.5 mg雌二醇及約0.25 mg屈螺酮(drospirenone)及至少一種醫藥學上可接受之賦形劑，及關於該劑型之包裝單位。該固體口服劑型可用於預防、治療或減輕女性血管舒縮症狀，降低女性突破性(breakthrough)出血頻率，或增加女性停經發生率。