Smith, Scott Andrew,Li, Xiaobin,Rossiter, Guillermo,Martin, Philippe L.,Dewacker, Seth R.,Usiskin, Keith,Cline, Gary Allan
申请号：
AU2015371325
公开号：
AU2015371325A1
申请日:
2015.12.23
申请国别(地区):
AU
年份:
2017
代理人:
摘要：
Described herein are methods of treating inflammatory bowel disease (I BD) in a patient having IBD using SMAD7 antisense oligonucleotides. In one aspect, provided herein is a method for treating or managing inflammatory bowel disease (IBD) in a patient having IBD, wherein the method comprises (a) administering to the patient a SMAD7 antisense-oligonucleotide (SMAD7 AON) during a first treatment period at a first dose； and (b) administering to the patient the SMAD7 antisense-oligonucleotide during a second treatment period at a second dose.
