PROBLEM TO BE SOLVED: To provide a novel pharmaceutical composition having antihypertensive action as well as heart rate lowering action.SOLUTION: The invention provides a pharmaceutical composition having antihypertensive action and heart rate lowering action, containing a Polygonum hydropiper dry substance and/or extract, and being used so that it is administered orally to a human at a dose of 10 mg/kg body weight/day or more based on the weight of the dry bud parts of Polygonum hydropiper. The preventive/therapeutic agent of hypertension has antihypertensive action as well as heart rate lowering action.COPYRIGHT: (C)2015,JPO&INPIT【課題】血圧降下作用と共に心拍数低下作用を有する新たな医薬組成物を提供する。【解決手段】ヤナギタデ乾燥物及び/又は抽出物を含有し、ヒトに対してヤナギタデ芽部の乾燥物の換算重量基準で10mg/kg体重/日以上を経口投与されるように用いられ、血圧降下作用及び心拍数低下作用を有する医薬組成物。当該高血圧症の予防治療剤は、血圧降下作用と共に、心拍数低下作用を有する。【選択図】なし