OLHAVA, EDWARD JAMES,CHESWORTH, RICHARD,KUNTZ, KEVIN WAYNE
申请号:
CA2819734
公开号:
CA2819734A1
申请日:
2011.12.05
申请国别(地区):
CA
年份:
2012
代理人:
摘要:
The present invention relates to carbocycle-substituted purine and 7-deazapurine compounds. The present invention also relates to pharmaceutical compositions containing these compounds and methods of treating disorders in which DOT1 -mediated protein methylation plays a part, such as cancer and neurological disorders, by administering these compounds and pharmaceutical compositions to subjects in need thereof.