COMPOSITION EXTERNE POUR LA PEAU CONTENANT DES DÉRIVÉS D'ORTHO-DIHYDROXYISOFLAVONE ET POUVANT EMPÊCHER L'HYPERPROLIFÉRATION ÉPIDERMIQUE ET ATTÉNUER LES AFFECTIONS CUTANÉES INFLAMMATOIRES
Disclosed herein is a skin external composition for inhibiting epidermal hyperproliferation and alleviating inflammatory skin diseases, which contains ortho-dihydroxyisoflavone derivatives as an active ingredient. Specifically, the skin external external composition contains the ortho-dihydroxyisoflavone derivatives, 4′,6,7-trihydroxyisoflavone, 3′,4′,7-trihydroxyisoflavone or a mixture thereof, and thus increases the expression of DKK3 protein and FZD1 protein, which appropriately control Wnt signaling, thereby inhibiting epidermal hyperproliferation and alleviating inflammatory skin diseases caused by epidermal hyperproliferation.