Sarah E. DOWDELL,Hilary Schenck EIDAM,Mark ELBAN,Ryan Michael FOX,Marlys HAMMOND,Mark A. HILFIKER,Tram H. HOANG,Lara KALLANDER,Brian Griffin LAWHORN,Sharada MANNS,Joanne PHILP,David G. WASHBURN,Guosen
申请号:
US15110776
公开号:
US20160340328A1
申请日:
2015.01.09
申请国别(地区):
US
年份:
2016
代理人:
摘要:
Disclosed are compounds having the formula:wherein R1, R2 and R3 are as defined herein, and methods of making and using the same, including use as inhibitors of BMP1, TLL1 and/or TLL2 and in treatment of diseases associated with BMP1, TLL1 and/or TLL2 activity.