WANG, HUI-LING,CEE, VICTOR J.,HERBERICH, BRADLEY J.,JACKSON, CLAIRE L. M.,LANMAN, BRIAN ALAN,NIXEY, THOMAS,PETTUS, LIPING H.,REED, ANTHONY B.,WU, BIN,WURZ, RYAN,TASKER, ANDREW
申请号：
CA2830780
公开号：
CA2830780A1
申请日:
2012.03.21
申请国别(地区):
CA
年份:
2012
代理人:
摘要：
The invention relates to bicyclic compounds of formulas I and Ia, and salts thereof. In some embodiments, the invention relates to inhibitors or modulators of Pim-1 and/or Pim-2, and/or Pim-3 protein kinase activity or enzyme function. In still further embodiments, the invention relates to pharmaceutical compositions comprising compounds disclosed herein, and their use in the prevention and treatment of Pim kinase related conditions and diseases, preferably cancer.
