Genentech, Inc.;F. Hoffmann-La Roche AG;Biogen Inc.
发明人:
Mark Totoritis,Timothy Mark Shaw,Sunil Agarwal,David Yocum,Ariella Kelman
申请号:
US16384333
公开号:
US20190270824A1
申请日:
2019.04.15
申请国别(地区):
US
年份:
2019
代理人:
摘要:
Methods of treating joint damage in a subject eligible for treatment are provided involving administering an antagonist that binds to a B-cell surface marker, such as CD20 antibody, to the subject in an amount effective to slow progression of the joint damage as measured by radiography. Further provided are articles of manufacture useful for such methods.