LABORATOIRE FRANCAIS DU FRACTIONNEMENT ET DES BIOTECHNOLOGIES;ETAT FRANCAIS REPRESENTE PAR LE DIRECTEUR CENTRAL DU SERVICE DE SANTE DES ARMEES
发明人:
Christian Behrens,Philippe Klein,Denis Hoguet
申请号：
US15111256
公开号：
US10059760B2
申请日:
2015.01.16
申请国别(地区):
US
年份:
2018
代理人:
摘要：
The present invention relates to a class-G immunoglobulin against the anthrax toxin protective antigen (PA), or one of the fragments of same, comprising at least: a variable heavy-chain region comprising an amino acid sequence represented by the sequence SEQ ID NO: 1, or comprising an amino acid sequence having at least 90% identity with the sequence SEQ ID NO: 1, and comprising the amino acids Leucine in position 51 and Glycine in position 67, and a variable light-chain region comprising an amino acid sequence represented by the sequence SEQ ID NO: 2, or comprising an amino acid sequence having at least 90% identity with the sequence SEQ ID NO: 2, and comprising a Leucine amino acid in position 55. The invention also relates to the uses of such an immunoglobulin.
