1 DR CHAVA SATYANARAYANA,2 DR GORACTLA SEETA RAMANJANEYULU,3 DR CHAVAKULA RAMDAS,4 MR KONUDULA BABU RAO
申请号:
IN993/CHE/2005
公开号:
IN299757B
申请日:
2005.07.25
申请国别(地区):
IN
年份:
2018
代理人:
摘要:
The present invention encompasses a method for the preparation of Almotriptan and its pharmaceutically acceptable salts comprises, i) Methylation of 3- 5-(l- Pyrrolidinyl sulfonyl methyl) lH-indol-yl ethane amine ii) Treating crude Almotriptan with a hydroxy benzoic acid yields hydroxy benzoic acid addition salt of Almotriptan iii) Converting Almotriptan hydroxy benzoic acid addition salt to Almotriptan and iv) Salification of Almotriptan to its pharmaceutically acceptable salts WO2007013098A1