Liming Shao,Fengjiang Wang,Scott C. Malcolm,Michael C. Hewitt
申请号:
US15817760
公开号:
US20180148407A1
申请日:
2017.11.20
申请国别(地区):
US
年份:
2018
代理人:
摘要:
Provided herein are bicyclic compounds and methods of synthesis thereof. The compounds provided herein are useful for the treatment, prevention, and/or management of various neurological disorders. Compounds provided herein inhibit reuptake of endogenous monoamines, such as dopamine, serotonin and norepinephrine (e.g., from the synaptic cleft) and modulate one or more monoamine transporter. Pharmaceutical formulations containing the compounds are also provided.