Gerd Ritter;Sacha Gnjatic;Hiroyoshi Nishikawa;Lloyd J. Old;Jorge E. Galan
发明人:
Lloyd J. Old,Gerd Ritter,Hiroyoshi Nishikawa,Sacha Gnjatic,Jorge E. Galan
申请号:
US12083188
公开号:
US08357373B2
申请日:
2006.10.03
申请国别(地区):
US
年份:
2013
代理人:
摘要:
The invention relates to the use of the type III secretion system of bacteria to stimulate immune responses against tumor antigen(s) for treating antigen-loss variant tumors. Methods are provided for stimulating and/or increasing an immune response against tumor antigens. The invention also relates to the preparation of antigen presenting cells from peripheral blood mononuclear cells using bacteria having a type III secretion system.