ZEMEL, MICHAEL,GRINDSTAFF, E. DOUGLAS, II,BRUCKBAUER, ANTJE
申请号:
CA2841748
公开号:
CA2841748A1
申请日:
2012.07.13
申请国别(地区):
CA
年份:
2013
代理人:
摘要:
Compositions and methods useful for inducing an increase in fatty acid oxidation or mitochondrial biogenesis, reducing weight gain, inducing weight loss, or increasing Sirt 1, Sirt3, or AMPK activity are provided herein. Such compositions can contain synergizing amounts of a sirtuin-pathway activators, including but not limited to resveratrol, in combination with beta-hydroxymethylbutyrate (HMB), keto isocaproic acid (KIC), leucine, or combinations of HMB, KIC and leucine.