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Spiro amino compounds suitable for the treatment of inter alia sleep disorders and drug addiction
专利权人:
Rottapharm S.p.A.
发明人:
Stasi, Luigi Piero,Rovati, Lucio
申请号:
AU2010272548
公开号:
AU2010272548A1
申请日:
2010.07.15
申请国别(地区):
AU
年份:
2012
代理人:
摘要:
The invention concerns a spiro-amino compound of Formula (Vl) wherein m is 1 or 2 or 3, n is 1 or 2, R is selected from a 5- or 6-membered aromatic ring and a 5- or 6-membered heteroaromatic ring comprising 1 to 3 heteroatoms selected from S, O e N, such ring being substituted with one or two substituents selected from the group consisting of (C-C)alkyl, halogen, (C-C)cycloalkyloxy, (C-C)alkylcarbonyl, phenyl optionally substituted with one or more halogen atoms, a 5- or 6-membered heterocycle comprising at least one nitrogen atom; P is a substituent Q or COQ, wherein Q is selected from the group consisting of phenyl, pyridil, pyrimidil, quinolyl, isoquinolyl, quinoxalyl, benzofuranyl, imidazotriazolyl, being such Q optionally substituted with one or more substituents selected from the group consisting of (C-C)alkyl, halogen, trifluoromethyl, carbammido, methylcarbammido, carboxy, methylcarboxy or a pharmaceutically acceptable salt thereof.
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