METHOD OF ACCUMULATING ALLERGEN-SPECIFIC T CELL ANTIGEN DETERMINANT IN PLANT AND PLANT HAVING THE ANTIGEN DETERMINANT ACCUMULATED THEREIN

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专利权人:

NATIONAL INSTITUTE OF AGROBIOLOGICAL SCIENCES;TAKAIWA, FUMIO;TAKAGI, HIDENORI

发明人:

TAKAIWA, FUMIO,TAKAGI, HIDENORI

申请号：

WO2004JP05938

公开号：

WO2004094637(A1)

申请日:

2004.04.23

申请国别(地区):

世界知识产权组织国际局

年份:

2004

代理人:

摘要：

As techniques of accumulating a human T cell epitope in rice albumen, a method comprising accumulating a T cell epitope-attached peptide (7crp) directly in seeds, and a method comprising inserting 7crp into the variable region of glutelin, which is a major storage protein of rice, and expressing and accumulating the same as a part of the glutelin storage protein are developed. It is strongly expected that the rice capable of producing the T cell epitope-attached peptide thus developed would serve as a practically usable edible vaccine against cedar pollen allergy.

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