CENTRE HOSPITALIER UNIVERSITAIRE VAUDOIS;SIEMENS HEALTHCARE GMBH
发明人:
MARIO JOAO FARTARIA DE OLIVEIRA,TOBIAS KOBER,BENEDICTE MARECHAL,CRISTINA GRANZIERA,MERITXELL BACH CUADRA
申请号：
US16819402
公开号：
US20200294237A1
申请日:
2020.03.16
申请国别(地区):
US
年份:
2020
代理人:
摘要：
A system and a method monitor a biological process. The method includes obtaining an abnormal tissue mask from an abnormal tissue segmentation of an image of an object containing tissue to be analyzed, the image being acquired at a time t0 being a reference time point. Other images of the object are registered onto the abnormal tissue mask, the other images being acquired at other time points. Image contrasts of the other images are normalized with respect to the contrasts of the image acquired at the reference time point. The normalized images are subtracted for each available contrast in order to obtain difference images. A joint difference image is created by summing the previously obtained difference images. A biological process progression map is created by overlapping the abnormal tissue mask obtained and the joint difference image after applying a pre-defined threshold.
