Fundação Oswaldo Cruz (fiocruz) - Superintendência De Planejamento
发明人:
BOECHAT, Nubia,BASTOS, Mõnica Macedo,LOPES E SOUZA, Thiago Moreno,LEITE, Débora Inácio,BERNARDINO, Alice Maria Rolim
申请号:
EP16901168
公开号:
EP3456718A4
申请日:
2016.05.10
申请国别(地区):
EP
年份:
2019
代理人:
摘要:
This invention relates to HIV-inhibiting compounds consisting of other Formulae I, II or III isatin derivatives, as shown below (Formulae I, II and III), whereby in Formulae I, II and III, R 1 is selected from H, CH 3 or Cl; R 2 is selected from one of the following radicals: zidovudine, amprenavir or an acyclic phosphonate chain, as shown below. This invention also relates to the use and treatment method using the Formulae I, II and III compounds. According to this invention, these compounds are also used for the treatment of infections caused by HBV or co-infection caused by HIV and HBV.