BISPECIFIC HER2 ANTIBODIES

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专利权人:

LLC;MEDIMMUNE

发明人:

LI, JOHN,DIMASI, NAZZARENO,COATS, STEVEN,DAMSCHRODER, MELISSA,GAO, CHANGSHOU,RAINEY, GODFREY,GAO, CUIHUA,TOADER, DORIN,GINGIPALLI, LAKSHMAIAH,WANG, FENGJIANG,FLEMING, RYAN,BEZABEH, BINYAM,YUAN, ANDY,

申请号：

SG11201608192S

公开号：

SG11201608192SA

申请日:

2015.04.10

申请国别(地区):

SG

年份:

2016

代理人:

摘要：

The present invention relates to anti-HER2 binding molecules (e.g., antibodies and antigen binding fragments thereof), derived HER2-binding molecules (e.g., bispecific anti-HER2 antibodies), and antibody-drug conjugates (ADC) that bind the extracellular domain of the HER2 receptor. Also provided are pharmaceutical formulation comprising the disclosed compositions and method for the treating diseases associated with HER2-mediated signal transduction.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/