ARCARI, JOEL THOMAS,BHATTACHARYA, SAMIT KUMAR,BROSIUS, ARTHUR DOUGLAS,LUZZIO, MICHAEL JOSEPH,NELSON, KENDRA LOUISE,PAN, GONGHUA,SOUTHERS, JAMES ALFRED, JR.,WISHKA, DONN GREGORY,XIAO, JUN
申请号:
CA2634646
公开号:
CA2634646C
申请日:
2006.12.11
申请国别(地区):
CA
年份:
2012
代理人:
摘要:
The present invention relates to a compound of the Formula (I) or apharmaceutically acceptable salt thereof, wherein Ar is a group of Formula(II) and salts thereof. Such pyrimidine derivatives are useful in thetreatment of abnormal cell growth, such as cancer, in mammals. This inventionalso relates to a method of using such compounds in the treatment of abnormalcell growth in mammals, especially humans, and to pharmaceutical compositionscontaining such compounds.