Compositions comprenant de la thrombine et procédé pour leur manufacture

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专利权人:

CSL Behring GmbH

发明人:

Metzner, Hubert, Dr.,Schneider, Heinrich

申请号：

EP01103992.2

公开号：

EP1136084B1

申请日:

2001.02.20

申请国别(地区):

EP

年份:

2017

代理人:

摘要：

Thrombin composition, (A,) that contains a non-covalently bonded inhibitor (I) as stabilizer, is new. Independent claims are also included for the following: (1) preparing a thrombin composition (A') by recovering prothrombin from plasma (or its fraction), activating to thrombin, optionally further processing, purification by hydrophobic interaction chromatography (HIC)； and optionally inactivation or removal of viruses； and (2) (A') prepared this way.

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