Amine cationic lipids and uses thereof

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专利权人:

Inc.;Dicerna Pharmaceuticals

发明人:

Bob Dale Brown

申请号：

US15407512

公开号：

US10144725B2

申请日:

2017.01.17

申请国别(地区):

US

年份:

2018

代理人:

摘要：

The present invention relates to lipid compounds and uses thereof. In particular, the compounds include a class of cationic lipids having an amine moiety, such as an amino-amine or an amino-amide moiety. The lipid compounds are useful for in vivo or in vitro delivery of one or more agents (e.g., a polyanionic payload or an antisense payload, such as an RNAi agent).

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