John A. Rogers,Dae-Hyeong Kim,Fiorenzo Omenetto,David L. Kaplan,Brian Litt,Jonathan Viventi,Yonggang Huang,Jason Amsden
申请号：
US12892001
公开号：
US08666471B2
申请日:
2010.09.28
申请国别(地区):
US
年份:
2014
代理人:
摘要：
Provided herein are implantable biomedical devices, methods of administering implantable biomedical devices, methods of making implantable biomedical devices, and methods of using implantable biomedical devices to actuate a target tissue or sense a parameter associated with the target tissue in a biological environment. Each implantable biomedical device comprises a bioresorbable substrate, an electronic device having a plurality of inorganic semiconductor components supported by the bioresorbable substrate, and a barrier layer encapsulating at least a portion of the inorganic semiconductor components. Upon contact with a biological environment the bioresorbable substrate is at least partially resorbed, thereby establishing conformal contact between the implantable biomedical device and the target tissue in the biological environment.
