A operation mode selector (140) including a non-mechanical optical switch and/or an optical combiner, optically directs the non-ionizing electromagnetic therapeutic and/or diagnostic radiation to tumor site (101), through a radiation conductor. Independent claims are also included for the following: (1) interactive interstitial photodynamic tumor therapy and/or photothermal tumor therapy and/or tumor diagnosis; and (2) use of non-mechanical optical switches and/or optical combiners in system for interactive therapy and/or diagnosis of human or animal.