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Controlled release compositions based on block polymers
专利权人:
Biolex Therapeutics, Inc.;OctoPlus PolyActive Sciences B.V.
发明人:
Bechet, Anne Chantal,Van Dijkhuizen-Radersma, Riemke,Stigter, Martin,Bezemer, Jeroen Mattijs
申请号:
AU2010224413
公开号:
AU2010224413B2
申请日:
2010.09.24
申请国别(地区):
AU
年份:
2012
代理人:
摘要:
#$%^&*AU2010224413B220120322.pdf#####ABSTRACT The invention discloses a pharmaceutical composition for the controlled release of relatively toxic active compounds, in particular for bioactive proteins from the class of interferons. The composition comprises a biodegradable block copolymer constructed from 5 poly(ethylene glycol) terephthalate (PEGT) and poly(butylene terephthalate) (PBT). The composition is provided in the form of injectable microparticles, of an injectable liquid which may have self-gelling properties, or of a solid implant. The invention further provides a pharmaceutical kit comprising the composition, methods for preparing the composition, and the pharmaceutical uses relating thereto. 10
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