The present invention is related to sulfonamide derivatives of Formula (Ia)where the groups are as defined in the description, and use thereof inparticular for the treatment and/or prophylaxis of autoimmune disorders,inflammatory diseases, cardiovascular diseases, neurodegenerative diseases,cancer, respiratory diseases and fibrosis, including multiple sclerosis,arthritis, emphysema, chronic obstructive pulmonary disease, liver andpulmonary fibrosis.