1. The use of opioids capable of inhibiting cell proliferation of malignant tumors, to obtain a medicinal product for the treatment of patients with resistant malignant tumors. ! 2. The use according to claim 1, where the patient with a malignant tumor has at least one type of resistance from the following group: resistance to apoptosis, chemoresistance, and radio resistance. ! 3. The use according to claim 1, where the patient has either congenital or acquired resistance. ! 4. The use according to claim 1, where the patient has one or more of the following types of resistance:! i. resistance to apoptosis; ! ii. multidrug resistance; ! iii. anticancer drug resistance; ! iv. resistance to cytotoxic drug; ! v. resistance to reactive forms of oxygen; ! vi. resistance to DNA damaging agents; ! vii. resistance to toxic antibodies; ! viii. resistance to doxorubicin; ! ix. single or cross-resistance, in particular to one or more of the following drugs: methotrexate, cytarabine, cisplatin, etoposide, vincristine, paclitaxel (taxol), carboplatin, teniposide, dexamethasone, prednisolone, cyclophosphamide, ifosfamide, doxorubicin, epoxorubicin, epoxorubicin, mercaptopurine, fludarabine, 5-fluorouracil; ! x. radiation resistance (e.g. alpha, beta, gamma or Auger electrons). ! 5. The use according to any one of claims 1 to 4, wherein the patient suffers from at least one of the malignant tumors: leukemia, malignant brain tumor, melanoma, pancreatic cancer, breast cancer, bladder cancer, colon carcinoma1. Применение опиоидов, способных ингибировать пролиферацию клеток злокачественных опухолей, для получения лекарственного средства для лечения пациентов с устойчивой злокачественной опухолью. ! 2. Применение по п.1, где пациент со злокачественной опухолью обладает по меньшей мере одним видом устойчивости из следующей группы: устойчивость к апоптозу, химиоустойчивость, радиоустойчивость. ! 3. Применение по п.1, где пациент обладает либо врожденной, либо приобретенной устойчивостью