METHOD AND COMPOSITION FOR TREATING HEPATOCELLULAR CARCINOMA WITHOUT VIRAL INFECTION BY CONTROLLING THE LIPID HOMEOSTASIS

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专利权人:

NATIONAL HEALTH RESEARCH INSTITUTES

发明人:

Shih-Feng TSAI,Yung-Feng LIN,Ning HSU

申请号：

US16753670

公开号：

US20200239588A1

申请日:

2018.10.05

申请国别(地区):

US

年份:

2020

代理人:

摘要：

The present invention relates to a method and a pharmaceutical composition for treating an HCC negative for HBV/HCV, comprising administering a subject in need thereof an therapeutically effective amount of an inhibitory agent to control the genetic alteration of lipid homeostasis associated genes, including CD36 amplification and ABCG4 deletion. According to the present invention, medicines targeting the lipid metabolism pathways are developed to treat HCC patients with CD36 amplification and/or ABCG4 deletion.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/