Barbara R. HABERER,Therese J. DOWNEY,Ronald E. UTECHT
申请号:
US14777111
公开号:
US20160030413A1
申请日:
2014.03.14
申请国别(地区):
US
年份:
2016
代理人:
摘要:
Disclosed herein is a compound for use in a composition applied to a blood vessel, wherein the compound softens and/or disrupts the crystalline matrix of calcified plaque, as well as acutely restoring the vascular compliance at the treatment site of the blood vessel, while maintaining luminal gain during angioplasty. Methods of treatment comprising applying the disclosed composition are also disclosed. Plaque-softening compounds are also disclosed.