A treatment regimen for psoriasis includes administering to a patient diagnosed with psoriasis periodic doses of a combination including emodin and digoxin, or a combination of emodin, digoxin, Sheng Di Huang, Da Huang and Jin Yin Hua, or a combination of emodin, digoxin, Sheng Di Huang, Da Huang, Jin Yin Hua, Mu Dan Pi, Di Gu Pi, Xian He Cao and Chun Gen Pi.