Chuntharapai, Anan,Kim, Jin K.,Presta, Leonard G.,Stewart, Timothy
申请号:
AU2011200707
公开号:
AU2011200707B2
申请日:
2011.02.18
申请国别(地区):
AU
年份:
2013
代理人:
摘要:
#$%^&*AU2011200707B220130620.pdf#####ABSTRACT The present invention relates generally to the generation and characterization of neutralizing anti-IFN-a monoclonal antibodies with broad reactivity against various IFN-a subtypes. The invention further relates to the use of such anti-lFN-aX antibodies in the 5 diagnosis and treatment of disorders associated with increased expression of IFN-ca, in particular, autoimmune disorders such as insulin-dependent diabetes mellitus (IDDM) and systemic lupus erythematosus (SLE). 2570171_1 (GHMAIcr) 18-F, 112/8 CY) en. , LLL IL IL IL Z ___ __L ___ __ ____L_ ___-L___ ___ _ E0 U)V 00 c0 -0 z Nv LLA13 U-aJ~