PHARMACEUTICAL COMPOSITIONS FOR PREVENTION OR TREATMENT OF DISEASE CAUSING AGING OF VASCULAR ENDOTHELIAL CELL COMPRISING EXTRACT OF PHYSALIS ANGULATA

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专利权人:

RURAL DEVELOPMENT ADMINISTRATION);대한민국(농촌진흥청장);REPUBLIC OF KOREA(MANAGEMENT ;REPUBLIC OF KOREA(MANAGEMENT : RURAL DEVELOPMENT ADMINISTRATION)

发明人:

LEE, SEUNG EUN,이승은,KIM, GEUM SOOG,김금숙,NOH, HYUNG JUN,노형준,LEE, JEONG HOON,이정훈,CHOI, JAE HUN,최재훈,LEE, DAE YOUNG,이대영,KIM, SEUNG YU,김승유,SUNG, JUNG SOOK,성정숙,JANG, IN BOK,장인복,KIM, JAE RYONG,김재룡,LEE, SEUNG EUNKR,KIM, GEUM SOOGKR,NOH, HYUNG JUNKR,LEE, JEONG HOONKR,CHOI, JAE HUNKR,LEE, DAE YOUNGKR,KIM, SEUNG YUKR,SUNG, JUNG SOOKKR,JANG, IN BOKKR,KIM, JAE RYON

申请号：

KR1020140157952

公开号：

KR1020140145570A

申请日:

2014.11.13

申请国别(地区):

KR

年份:

2014

代理人:

摘要：

The present invention relates to a pharmaceutical composition comprising a Physalis angulata L. extract for preventing or treating diseases caused by vascular endothelial cell aging. Since the pharmaceutical composition comprising a Physalis angulata L. extract for preventing or treating diseases caused by vascular endothelial cell aging of the present invention can effectively enhance fibroblast or vascular endothelial cell proliferation and inhibit SA-&beta；-galactosidase activity to thereby suppress vascular endothelial cell aging, the composition can be useful to prevent diseases caused by vascular endothelial cell aging such as cardiovascular disease, chronic renal disease, chronic inflammatory dermatitis, atheroma inflammation, and Parkinson&prime；s disease.본 발명은 땅꽈리(Physalis angulata L.) 추출물을 포함하는 혈관내피세포 노화로 유발되는 질병의 예방 또는 치료용 약학적 조성물에 관한 것으로, 본 발명의 땅꽈리 열매 추출물을 포함하는 혈관내피세포 노화로 유발되는 질병의 예방 또는 치료용 약학적 조성물은 효과적으로 섬유아세포 또는 혈관내피 세포 증식을 향상시키고 SA-β-갈락토시다아제 활성 저해를 통한 혈관내피 세포 노화를 억제할 수 있으므로, 심혈관질환, 만성신장질환, 만성염증성 피부질환, 아테롬성 염증 및 파킨슨병 등과 같은 혈관내피세포 노화로 유발되는 질환의 예방에 유용하게 사용될 수 있다.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/