Stable liquid formulations of dimer VEGF antagonists

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专利权人:

Regeneron Pharmaceuticals; Inc.

发明人:

Daniel Dix,Kelly Frye,Susan Kautz

申请号：

US14550385

公开号：

US09416167B2

申请日:

2014.11.21

申请国别(地区):

US

年份:

2016

代理人:

摘要：

Formulations of a vascular endothelial growth factor (VEGF)-specific fusion protein antagonist are provided including a pre-lyophilized formulation, a reconstituted lyophilized formulation, and a stable liquid formulation. Preferably, the fusion protein has the sequence of SEQ ID NO:4.

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