Provided is a micro-current therapy device using high electric potential to provide high electric potential therapy by generating high electric potential as high voltage induced from a high-voltage transformer, and regulating micro-current of the generated high-electric potential. The micro-current therapy device supplies commercial AC power through a power unit. When a frequency operation signal is inputted through an operation unit, a control unit generates a relay control signal and a high-potential current control signal according to the frequency set by the operation unit. A relay unit supplies or cuts off the commercial AC power supplied from the power unit according to the relay control signal. A high-voltage output unit outputs a high electric potential by boosting up the commercial AC power outputted from the relay unit. A current regulating unit regulates the high electric potential current, thereby applying the optimized high electric potential to a therapy part of a user.
