102 124 104 122 108 (12) INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property Organization International Bureau (43) International Publication Date 26 July 2018 (26.07.2018) WIPO I PCT omit VIII °nolo ollimoimo IID No oimIE (10) International Publication Number WO 2018/136971 Al (51) International Patent Classification: A61F 2/24 (2006.01) (21) International Application Number: PCT/US2018/014918 (22) International Filing Date: 23 January 2018 (23.01.2018) (25) Filing Language: English (26) Publication Language: English (30) Priority Data: 62/449,320 23 January 2017 (23.01.2017) US 62/520,703 16 June 2017 (16.06.2017) US 62/535,724 21 July 2017 (21.07.2017) US 15/876,053 19 January 2018 (19.01.2018) US (71) Applicant: EDWARDS LIFESCIENCES CORPO- RATION [US/US]； One Edwards Way, Irvine, CA 92614 (US). (72) Inventors: HAIVATOV, Sara； Edwards Lifesciences, One Edwards Way, Legal Department, Irvine, CA 92614 (US). PERLMUTTER, Khen； Edwards Lifesciences, One Edwards Way, Legal Department, Irvine, CA 92614 (US). PATEL, Darshin, S.； Edwards Lifesciences, One Edwards Way, Legal Department, Irvine, CA 92614 (US). MAN- ASH, Boaz； Edwards Lifesciences, One Edwards Way, Le- gal Department, Irvine, CA 92614 (US). CHADHA, Ajay； Edwards Lifesciences, One Edwards Way, Legal Depart- ment, Irvine, CA 92614 (US). CHU, Waina, Michelle； Edwards Lifesciences, One Edwards Way, Legal Depart- ment, Irvine, CA 92614 (US). CHHE, Chambory； Ed- wards Lifesciences, One Edwards Way, Legal Department, Irvine, CA 92614 (US). SCHWARTZ, Evan, T.； Edwards Lifesciences, One Edwards Way, Legal Department, Irvine, CA 92614 (US). PAWAR, Sandip, Vasant； Edwards Life- sciences, One Edwards Way, Legal Department, Irvine, CA 92614 (US). (74) Agent: GERMAN, Joel, B. et al.； Edwards Lifesciences, One Edwards Way, Irvine, CA 92614 (US). (81) Designated States (unless otherwise indicated, for every kind of national protection available): AE, AG, AL, AM, AO,
