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Dermal delivery device with reduced loss of its volatile components
专利权人:
Agis Kydonieus
发明人:
Agis Kydonieus,Robert G. Conway,Thomas M. Rossi
申请号:
US12668322
公开号:
US08246978B2
申请日:
2008.07.10
申请国别(地区):
US
年份:
2012
代理人:
摘要:
This invention relates to a transdermal drug delivery device that comprises an active ingredient (AI) layer, having a skin contacting surface and a non-skin contacting surface and comprising a volatile component, a release liner impermeable to the volatile component adjacent the skin contacting surface of the AI layer having a perimeter that extends beyond the perimeter of the AI layer in all directions, and an overlay comprising a pressure sensitive adhesive (PSA) that does not absorb the volatile component adjacent the non-skin contacting surface of the AI layer having a perimeter of which extends beyond the perimeter of the AI layer in all directions, wherein the release liner and the PSA of the overlay are in contact with and adhered to each other around the perimeter of the AI layer to form a seal that reduces or prevents volatile component loss.
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