The present invention relates to an ophthalmic composition containing cyclosporine as an active ingredient and comprising propylene glycol, a surfactant, and purified water, and to a method for preparing same. The ophthalmic composition according to the present invention is in the form of a clear and transparent solution, and increases patient compliance due to the absence of side effects, such as cloudy vision or a scorching sensation, and has a high bioavailability due to improved cyclosporine absorbance in the ocular tissue, which is the target organ.La présente invention concerne une composition ophtalmique contenant de la cyclosporine comme principe actif et comprenant du propylène glycol, un tensio-actif et de leau purifiée, et un procédé pour sa préparation. La composition ophtalmique selon la présente invention est sous la forme dune solution claire et transparente et améliore lobservance du traitement par un patient en raison de labsence deffets secondaires, tels que la vision trouble ou une sensation de brûlure, et a une biodisponibilité élevée en raison de labsorbance de cyclosporine améliorée dans le tissu oculaire, qui est lorgane cible.본 발명은 유효성분으로 사이클로스포린을 함유하며, 프로필렌글리콜, 계면활성제 및 정제수를 포함하는 안약 조성물 및 그 제조방법에 관한 것으로, 본 발명의 안약 조성물은 맑고 투명한 용액형태로서, 시야 흐림, 작열감 등의 부작용이 없어 환자의 복약순응도가 증대되고, 표적 기관인 안구조직으로의 사이클로스포린의 흡수가 개선되어 생체 이용성이 높다.
