Injectable Pharmaceutical composition comprising ibuprofen, an aqueous solution and a solubilizing Agent is selected from Sodium Phosphates, carbonates of potassium, sodium, potassium and / or combinations of them.
The present invention provides a pharmaceutical composition comprising an aqueous solution of an ibuprofen solubilizing agent and ibuprofen, the ibuprofen solubilizing agent being in an effective amount such that the ibuprofen in the solution remains soluble at concentrations from lOOmg/mL to 5mg/mL without undergoing a phase transition. The invention further provides a method of treating a condition chosen from pain, inflammation, fever, and/or patent ductus arteriosis, comprising administering to a patient in need thereof an effective amount of an aqueous solution a ibuprofen solubilizing agent and ibuprofen, the ibuprofen solubilizing agent being in an effective amount such that the ibuprofen in the solution remains soluble at concentrations from lOOmg/mL to 5mg/mL without undergoing a phase transition, as well as a method for manufacturing the composition.<;p>;COMPOSICION FARMACEUTICA INYECTABLE QUE COMPRENDE IBUPROFENO, UNA SOLUCION ACUOSA Y UN AGENTE SOLUBILIZANTE SELECCIONADO DE FOSFATOS DE SODIO, DE POTASIO, CARBONATOS DE SODIO, DE POTASIO Y/O COMBINACIONES DE ELLOS.<;/p>;