A bottle of single use (1) for dispensing an aqueous nutritional composition (5a) for a human, from a nutritional base formula (5) in powder or liquid concentrate contained therein, comprising the bottle ( 1) at least one compartment (3) forming a cavity for containing a predetermined amount of base formula nutrient (5) in powder or a concentrated liquid for preparing the nutritional composition (5a) after hydration with supplied, a neck portion (4) in fluid communication with the compartment (3), and a means for liquid inlet (6) designed to be fed with liquid from the dispensing means liquid (20), liquid bottle (1) further comprises a filter assembly (7) in the flow path of liquid from the inlet means (6) to the compartment (3), the filter assembly being configured to remove contaminants from the feed liquid in the compartment (3) through the inlet means (6), characterized in that, the bottle is further provided with a connecting means (2) adapted to connect the bottle (1) to an external medium dispensing liquid (20) adapted for supplying liquid to the bottle (1) wherein said connecting means (2) 15 at least one protrusion and / or recess formed in the neck portion (4) and / or a body portion of the bottle.Un biberón de un solo uso (1) para la dispensación de una composición nutritiva acuosa (5a) para un humano, a partir de una fórmula base nutritiva (5) en polvo o en un líquido concentrado contenido en el mismo, comprendiendo la botella (1) por lo menos un compartimento (3) que forma una cavidad para contener una cantidad predeterminada de fórmula base nutritiva (5) en polvo o en un líquido concentrado, para la preparación de la composición nutritiva (5a) después de la hidratación con el líquido suministrado, una porción de cuello (4) en comunicación fluida con el compartimento (3), y un medio para la entrada de líquido (6) diseñado para ser alimentado con líquido desde el medio de dispensación de líquido (20), la botella (1) comprende además, un conjunto filtrant