A method of inhibiting an overactive fibroblast growth factor receptor 3 (FGFR3) in a cell by contacting the cell with a composition that contains an effective amount of Pheophorbide a, Pyropheophorbide a, or an active derivative thereof. Also disclosed is a method for treating a disorder associated with an overactive FGFR3 with a composition containing an effective amount of Pheophorbide a, Pyropheophorbide a, or an active derivative thereof. Further, a composition for treating a disorder associated with an overactive FGFR3 is described. The composition contains an ethanol extract ofAmaranthusviridis.一種抑制纖維母細胞生長因子受體3 (fibroblast growth factor receptor 3, FGFR3) 在細胞中過度活化的方法,係透過將該細胞與含有有效量之去鎂葉綠素酸a、焦去鎂葉綠素酸a、或其活性衍生物的組合物接觸。還公開一種以含有有效量之去鎂葉綠素酸a、焦去鎂葉綠素酸a、或其活性衍生物的組合物治療FGFR3過度活化相關的病症之方法。此外,描述了一種用於治療FGFR3過度活化相關的病症之組合物。該組合物含有莧菜之乙醇萃取物。