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具有經微結構所調介之吸收概貌之裝置
专利权人:
BVW HOLDING AG
发明人:
MILBOCKER, MICHAEL,弥巴克 麦可,彌巴克 麥可,BLUECHER, LUKAS,布鲁契 鲁卡斯,布魯契 魯卡斯,KLEINHEINZ, KENNETH,克雷汉兹 肯尼斯,克雷漢茲 肯尼斯
申请号:
TW107136807
公开号:
TW201932145A
申请日:
2018.10.18
申请国别(地区):
TW
年份:
2019
代理人:
摘要:
Polymer devices are disclosed with surface microstructure that modifies their absorption pathway. Polymers which generally degrade in water by fracturing into high surface energy fragments, are modified to degrade without the formation of sharp fragments. Devices are disclosed that possess improved handling characteristics and degrade in an aqueous environment in a uniform and continuous way that favors the formation of soluble monomers rather than solid particulate. Absorbable medical implants with the disclosed surface modifications are more biocompatible, with reduced foreign body response, and dissolution into metabolizable molecular species. The present invention provides a surgical implant which is made of a polymer that degrades into polymeric monomers while implanted in tissue. The surgical implant has a preferential degradation zone adapted to hydrate at a different rate than the rest of the surgical implant.本申請案揭露具有修飾其吸收路徑的表面微結構之聚合物裝置。通常藉由破碎成高表面能片段而在水中降解的聚合物經修飾以降解而不形成尖銳的片段。本申請案揭露具有改良的處理特性並在水性環境中以均勻且連續的方式降解之裝置,其有利於形成可溶性單體而不是固體顆粒。具有所揭露的表面修飾之可吸收的醫用植入物更具生物相容性,具有降低的異物反應且溶解成可代謝的分子種類。本發明提供外科植入物,其是由聚合物製成,該聚合物在植入組織中時降解成聚合物單體。該外科植入物具有優先降解區,其適於以與該外科植入物的其餘部分不同的速率水合。
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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