Lysosome-cleavable linker
- 专利权人:
- UCL Business PLC
- 发明人:
- Mark Edward Brennan Smith
- 申请号：
- US14378138
- 公开号：
- US10010623B2
- 申请日:
- 2013.02.05
- 申请国别(地区):
- US
- 年份:
- 2018
- 代理人:
- 摘要：
- The present invention relates to a linker for forming conjugates of a protein or peptide with a therapeutically active agent and which comprise a thiomaleamic acid moiety that is susceptible to cleavage under the pH conditions prevalent in the lysosome.
- 来源网站：
- 中国工程科技知识中心
