NEW PROCESS FOR SYNTHESIS OF (2E)-3-(3,4-DIMETHOXYPHENYL) PROP-2-ENENITRILE, AND APPLICATION IN SYNTHESIS OF IVABRADINE AND ADDITION SALTS THEREWITH PHARMACEUTICALLY ACCEPTABLE ACID
CARRANZA, MARIA DEL PILAR,GARCIA ARANDA, MARIA ISABEL,GONZALEZ, JOSE LORENZO,SANCHEZ, FREDERIC
申请号:
GEAP2013013282
公开号:
GEP20156308B
申请日:
2013.11.05
申请国别(地区):
GE
年份:
2015
代理人:
摘要:
There are represented (2E)-3-(3,4-dimetho¬xyphenyl)prop-2-enenitrile of formula (I), new method of synthesis thereof, and application therefor synthesis of ivabradine and pharmace¬utically acceptable salts thereof.