The invention relates to a nutritional connposition for infants and young children, such as an infant formula or follow-on formula or growing up milk, preferably an infant formula, and comprising choline. The choline promotes and/or supports an ideal myelination trajectory in the brain, such trajectory being close to that observed in infants fed exclusively with human breast milk (HBM). The infants or young children can be between 0 and 60 months, preferably between 0 and 12 months of age.