ALTON Eric Walter Frederick Wolfgang,GRIESENBACH Uta,PYTEL Kamila Malgorzata,PAUL-SMITH Michael Christian,PRINGLE Ian Andrew,HYDE Stephen Charles,GILL Deborah Rebecca,DAVIES Lee Adrian,BOYD Alan Chris
申请号:
SI201531275
公开号:
SI3145949T1
申请日:
2015.04.23
申请国别(地区):
SI
年份:
2020
代理人:
摘要:
This invention relates to lentiviral gene transfer vectors pseudotyped with hemagglutinin-neuraminidase (HN) and fusion (F) proteins from a respiratory paramyxovirus, comprising a promoter and a transgene; and methods of making the same. The present invention also relates to the use of said vectors in gene therapy, particularly for the treatment of respiratory tract diseases such as Cystic Fibrosis (CF).