An apparatus configured to disinfect an intravenous (IV) access port is disclosed. The apparatus has at least one sterilizing cap with a body configured to removably couple to the access port and an illuminator coupled to the body. The body and illuminator are configured to expose at least one surface of the access port to a dose of ultraviolet (UV) light. In certain embodiments, the illuminator includes a source of UV light, such as a light-emitting diode (LED). In certain embodiments, the illuminator receives the UV light from a remote source through a fiber-optic cable.
